Endocrine Abstracts

Introduction: Bisphosphonates (BP) have been employed for many years and have demonstrated an excellent safety profile. Nevertheless, severe osteonecrosis of the jaw (ONJ) have been described in patients with bone metastases that were treated with BP for many years.Case: A 72 year old female with breast cancer and bone metastases treated with quadrantectomy, axillary lymph node dissection, radiotherapy, tamoxifen and pamidronate 90 mg/month. Two years la...